Last year, a Chinese woman paid in excess of USD500k for a Tibetan Mastiff... Article here:http://www.dailyfinance.com/story/tibetan-mastiff-becomes-worlds-priciest-dog-chinese-woman-pays/19159153/I've met and trained with TWO pure-bred mastiffs which are quite rare and I've walked past a house (in China) with 5 all-black Mastiffs that shocked the living soul outta me......I've seen these dogs as pups; and they learn just the same as other dogs. The science applies the same. However, when it comes to animals, there is always that little 'connection, feeling and/or sense' that brings out each animal to what they truly are.In the case of the Tibetan Mastiff, what I've seen, is that they have a very very strong bond with their immediate family like most guardian type dogs are. That's not to say there are exceptions, but in terms of training; it's more of socialisation (letting the dog know that people in this world are friendly) and habituation to everyday environments (to get them used to unfamiliar sounds/sights/places e.g. microwave sounds, telephones, doorbells etc). That is all more important than the conventional 'sit/down/stay' (which is still important also)Of course, their natural instincts and personality will kick in as they grow up; but we can do our best to make things easier.The picture below is of one of my client's dog - he was living with a family of four with two twin girls and a second dog. (Learnt to poo outside in ONE day).